The Environmental Toxicology group has received a grant of €100,000 from the National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3R), one of the largest organizations against animal experimentation, to prepare a proposal project for the next three years to develop a suite of innovative, scalable bioassays for key adverse outcome pathways to replace in fish studies in chemical safety screening and regulatory environmental risk assessment. This is phase 1 of the NC3R Challenge SAFE.
The project FishOnChip, whose PI is Dr. Carlos Barata, aims to develop innovative and marketable solutions to minimize fish testing to determine environmental toxicity of chemicals by using cell culture, transcriptomics, microelectronics, and microfluidic technologies to develop multi-cellular in vitro system that allows detecting molecular responses related to adverse effects on fish.
This proposal will finish in June 2022 and it is sponsored by AstraZeneca, Bayer AG, and Unilever. It has also a partnership with DEFRA, Health and Safety Executive, and the Environment Agency.
IDAEA-CSIC Communication
